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Berberine HCl CAS 633-65-8 Instruction
◆ Natural Berberine, an important alkaloid, which can be extracted from plants like berberine, cork, and three needles. It has a remarkable bacteriostatic effect. With richful berberine hcl, the commonly used berberine hydrochloride is also called berberine hcl extract.
◆ Berberine is an important alkaloid that can be extracted from plants such as Coptis chinensis, Phellodendron chinense, and Berberis virgetorum. It has significant antibacterial effect. The commonly used berberine hydrochloride is also called berberine hydrochloride. Berberine can resist pathogenic microorganisms, and it can inhibit a variety of bacteria such as dysentery bacillus, tuberculosis bacilli, pneumococcus, typhoid bacillus, and diphtheria bacillus, among which the bacterium has the strongest effect on dysentery bacillus, which is commonly used to treat bacterial gastroenteritis and dysentery Waiting for digestive diseases. Clinically, it is mainly used to treat bacterial dysentery and gastroenteritis. It has no drug resistance and side effects.
Specification of Berberine hcl CP2010
ITEMS |
SPECIFICATIONS |
METHOD/STANDARD |
Characters |
Powder |
Organoleptic |
Color |
Yellow or Orange powder |
Organoleptic |
Extract solvent |
Ethanol & Water |
-- |
Loss on drying |
≤12.0% |
CP2010 |
Residue on Ignition |
≤0.2% |
CP2010 |
Cyanide |
None |
CP2010 |
Organic nitrile |
None |
CP2010 |
Bulk Density |
50-60g/100ml |
-- |
Solvent Residue |
Eur.Pharm |
-- |
Pesticide Residue |
Negative |
-- |
Identification: |
By HPLC/TLC/Titration |
|
Assay (On dry basis) |
≥90.0% Berberine hcl |
HPLC |
≥97.0% Berberine hcl |
Titration |
|
Heavy Metals |
≤10.0ppm |
CP2010 |
Pb |
≤1.0ppm |
CP2010 |
As |
≤1.0ppm |
CP2010 |
Hg |
≤0.1ppm |
CP2010 |
Cd |
≤0.2ppm |
CP2010 |
Microbiological |
||
Total Plate Count |
1000cfu/g Max |
CP2010 |
Yeast&Mold |
100cfu/g Max |
CP2010 |
E.Coli colonies/g |
Negative (-) |
CP2010 |
Samonella colonies/g |
Negative (-) |
CP2010 |
Product benefits
◆ Berberine HCl CAS 633-65-8 has an obvious hypolipidemic effect: Clinical observations show that in patients with hypercholesterolemia treated with berberine, total cholesterol, cholesterol, low-density lipoprotein and triglyceride decreased by 20% after oral administration of berberine for 3 months ~ 28%.
◆ Phellodendron extract has a hypoglycemic effect: Diabetic patients take 0.4 g orally 4 times a day, after taking 1 to 3 months, it may reduce blood sugar to normal levels.
◆ Other benefits of Berberine extract.
Berberine's antihypertensive effect is also very good: most elderly patients with hypertension can take their blood pressure to a normal range after taking this medicine. This is because berberine in berberine can directly act on vascular smooth muscle and has a vasodilator effect.
Berberine HCl CAS 633-65-8 Application
Berberine has been used as an over-the-counter drug in the treatment of diarrhea in clinic, but modern pharmacological studies have confirmed that berberine has significant anti-heart failure, anti-arrhythmia, lower cholesterol, anti-vascular smooth muscle proliferation, improve insulin resistance, anti-platelet, anti-inflammatory And other functions, so it may have broad and important application prospects in cardiovascular system and nervous system diseases, which are increasingly valued.
Recommended dosage
◆ For diabetes: 0.9 to 1.5 grams of berberine hcl daily, 2-4 months.
◆ For high cholesterol: 0.6 to 1.5 grams of berberine hcl daily, 2-12 months.
◆ For high blood pressure: 0.9 grams of berberine hcl daily, 2 months.
Manufacturing process
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